ΕΠΙΛΕΓΜΕΝΕΣ ΔΗΜΟΣΙΕΥΣΕΙΣ

2013

  • Castana O, Dimitrouli A, Argyrakos T, Theodorakopoulou E, Stampolidis N, Papadopoulos E, Pallantzas A, Stasinopoulos I and Poulas K. Wireless Electrical Stimulation : An Innovative Powerful Tool for the Treatment of a Complicated Chronic Ulcer, The International Journal of Lower Extremity Wounds, DOI: 10.1177/1534734613476517.
  • Ramadhinara A, Poulas K. Use of wireless microcurrent stimulation for the treatment of diabetes-related wounds: 2 case reports. Adv Skin Wound Care; 26(1):1-4.
  • Kambouris M, Velegraki A, Patrinos G and Poulas K. “The Combination of Aerobiology, Morphology and Genetic Manipulation of Fungal Spores Constitutes the Ultimate Biosecurity Threat”. Journal of Life Sciences. Accepted for publication.
  • Radmilovic M, Zukic B, Petrovic MS, Bartsakoulia M, Stankovic B, Kotur N, Dokmanovic L, Georgitsi M, Patrinos GP, Pavlovic S. Functional analysis of a novel KLF1 gene promoter variation associated with hereditary persistence of fetal hemoglobin. Ann Hematol 92: 53-58.

2012

  • Lazaridis K, Zisimopoulou P, Lagoumintzis G, Skriapa L, Trakas N, Evangelakou P, Kanelopoulos I, Grapsa E, Poulas K, Tzartos S. Antigen-specific apheresis of autoantibodies in myasthenia gravis. Ann N Y Acad Sci; 1275(1):7-12.
  • Borg J, Phylactides M, Bartsakoulia M, Tafrali C, Lederer C, Felice AE, Papachatzopoulou A, Kourakli A, Stavrou EF, Christou S, Hou J, Karkabouna S, Lappa-Manakou C, Ozgur Z, van Ijcken W, von Lindern M, Grosveld FG, Georgitsi M, Kleanthous M, Philipsen S, Patrinos GP. KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients. Pharmacogenomics; 13: 1487-1500.
  • Giannopoulou E, Bartsakoulia M, Tafrali C, Kourakli A, Poulas K, Stavrou EF, Papachatzopoulou A, Georgitsi M, Patrinos GP. A single nucleotide polymorphism in the HBBP1 gene in the human β-globin locus is associated with a mild β-thalassemia disease phenotype. Hemoglobin; 36(5):433-45.
  • Kotur N, Stankovic B, Kassela K, Georgitsi M, Vicha A, Leontari I, Dokmanovic L, Janic D, Krstovski N, Klaassen K, Radmilovic M, Stojiljkovic M, Nikcevic G, Simeonidis A, Sivolapenko G, Pavlovic S, Patrinos GP, Zukic B. 6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner. Pharmacogenomics; 13: 283-295.
  • Poulas K, Koutsouraki E, Kordas G, Kokla A, Tzartos SJ. Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by d-penicillamine. J Neuroimmunol; 15;250(1-2):94-8.
  • Viennas E, Gkantouna V, Ioannou M, Georgitsi M, Rigou M, Poulas K, Patrinos GP, Tzimas G. Population-ethnic group specific genome variation allele frequency data: a querying and visualization journey. Genomics; 100(2):93-101.
  • Zagoriti Z, Georgitsi M, Giannakopoulou O, Ntellos F, Tzartos SJ, Patrinos GP, Poulas K. Genetics of myasthenia gravis: a case-control association study in the Hellenic population. Clin Dev Immunol; 48:491-9.

2011

  • Dalgleish R, Oetting WS, Auerbach AD, Beckmann JS, Cambon‐Thomsen A, Devereau A, Greenblatt MS, Patrinos GP, Taylor GR, Vihinen M, Brookes AJ. Clarity and claims in variation/mutation databasing. Nature Biotechnol 29: 790-792.
  • Kricka LJ, Fortina P, Mai Y, Patrinos GP. Direct-to-consumer genetic testing: A view from Europe. Nature Rev Genet 12: 670.
  • Squassina A, Manchia M, Borg J, Congiu D, Costa M, Georgitsi M, Chillotti C, Ardau R, Mitropoulos K, Severino G, Del Zompo M, Patrinos GP. Evidence for association of an ACCN1 gene variant with response to lithium treatment in Sardinian patients with bipolar disorder. Pharmacogenomics 12: 1559-1569.
  • Giardine B, Borg J, Higgs DR, Peterson KR, Philipsen S, Maglott D, Singleton BK, Anstee DJ, Basak AN, Clark B, Costa FC, Faustino P, Fedosyuk H, Felice AE, Francina A, Galanello R, Gallivan MV, Georgitsi M, Gibbons RJ, Giordano PC, Harteveld CL, Hoyer JD, Jarvis M, Joly P, Kanavakis E, Kollia P, Menzel S, Miller W, Moradkhani K, Old J, Papachatzopoulou A, Papadakis MN, Papadopoulos P, Pavlovic S, Perseu L, Radmilovic M, Riemer C, Satta S, Schrijver I, Stojiljkovic M, Thein SL, Traeger-Synodinos J, Tully R, Wada T, Waye JS, Wiemann C, Zukic B, Chui DH, Wajcman H, Hardison RC, Patrinos GP. Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach. Nature Genet 43: 295-301.
  • Georgitsi M, Viennas E, Gkantouna V, Christodoulopoulou E, Zagoriti Z, Tafrali C, Ntellos F, Giannakopoulou O, Boulakou A, Vlahopoulou P, Kyriacou E, Tsaknakis J, Tsakalidis A, Poulas K, Tzimas G, Patrinos GP. Population-specific documentation of pharmacogenomic markers and their allelic frequencies in FINDbase. Pharmacogenomics; 12(1):49-58.
  • Satra M, Samara M, Wosniak G, Tzavara C, Kontos A, Valotassiou V, Vamvakopoulos NK, Tsougos G, Aleporou-Marinou V, Patrinos GP, Kollia P, Georgoulias P. Sequence variations in the FII, FV, F13A1, FGB and PAI-1 genes are associated with differences in myocardial perfusion. Pharmacogenomics 12: 195-203.
  • Georgitsi M, Viennas E, Antoniou DI, Gkantouna V, van Baal S, Petricoin EF 3rd, Poulas K, Tzimas G, Patrinos GP. FINDbase: a worldwide database for genetic variation allele frequencies updated. Nucleic Acids Res; 39 (Database issue):D926-32.
  • Dimitropoulos N, Papakyriakou A, Dalkas GA, Chasapis CT, Poulas K, Spyroulias GA. A computational investigation on the role of glycosylation in the binding ofalpha1 nicotinic acetylcholine receptor with two alpha-neurotoxins. Proteins.2011 Jan;79(1):142-52.

2010

  • Borg J, Papadopoulos P, Georgitsi M, Gutierrez L, Grech G, Fanis P, Phylactides M, Verkerk AJ, van der Spek PJ, Scerri CA, Cassar W, Galdies R, van Ijcken W, Özgür Z, Gillemans N, Hou J, Grosveld FG, von Lindern M, Felice AE, Patrinos GP, Philipsen S. Haploinsufficiency for the erythroid transcription factor KLF1 causes Hereditary Persistence of Fetal Hemoglobin. Nature Genetics 42: 801-805.
  • Squassina A, Artac M, Manolopoulos VG, Karkabouna S, Lappa-Manakou C, Mitropoulos K, Manchia M, del Zompo M, Patrinos GP. Translation of genetic knowledge into clinical practice: the expectations and realities of pharmacogenomics and personalized medicine. Pharmacogenomics 11: 1149-1167
  • Zukic B, Radmilovic M, Stojiljkovic M, Tosic N, Pourfarzad F, Dokmanovic L, Janic D, Colovic N, Philipsen S, Patrinos GP, Pavlovic S. Functional analysis of the role of TPMT gene promoter VNTR polymorphism in TPMT gene transcription. Pharmacogenomics 11: 547-557.
  • Voutsinas GE, Stavrou EF, Karousos G, Dasoula A, Papachatzopoulou A, Syrrou M, Verkerk AJMH, van der Spek P, Patrinos GP, Stöger R, Athanassiadou A. Allelic imbalance of expression and epigenetic regulation within the alpha-synuclein wt and c.209G>A gene alleles in Parkinson's Disease. Hum Mutat 31: 685-691.
  • van Baal S, Zlotogora J, Lagoumintzis G, Gkantouna V, Tzimas I, Poulas K, Tsakalidis A, Romeo G, Patrinos GP. ETHNOS : A versatile electronic tool for the development and curation of national genetic databases. Hum Genomics. 2010 Jun;4(5):361-8.
  • Lagoumintzis G, Poulas K, Patrinos GP. Genetic databases and their potential in pharmacogenomics. Curr Pharm Des. 2010;16(20):2224-31.
  • Lagoumintzis G, Zisimopoulou P, Kordas G, Lazaridis K, Poulas K, Tzartos SJ. Recent approaches to the development of antigen-specific immunotherapies for myasthenia gravis. Autoimmunity; 43(5-6):436-45.

2009

  • Tsiamalos P, Kordas G, Kokla A, Poulas K, Tzartos SJ. Epidemiological and immunological profile of muscle-specific kinase myasthenia gravis in Greece. Eur J Neurol; 16(8):925-30.
  • Chuzhanova N, Chen JM, Bacolla A, Patrinos GP, Férec C, Wells RD, Cooper DN. Gene conversion causing human inherited disease: evidence for involvement of non-B-DNA-forming sequences and recombination-promoting motifs in DNA breakage and repair. Hum Mutat 30: 1189-1198. (pdf)
  • Moradkhani K, Préhu C, Old J, Henderson S, Balamitsa V, Luo HY, Poon MC, Chui DH, Wajcman H,Patrinos GP . (2009). Mutations in the paralogous human α-globin genes yielding identical hemoglobin variants. Ann Hematol 88: 535-543. (pdf)
  • Zouridakis M, Zisimopoulou P, Poulas K, Tzartos SJ. Recent advances in understanding the structure of nicotinic acetylcholine receptors. IUBMB Life; 61(4):407-23.
  • Zouridakis M, Zisimopoulou P, Eliopoulos E, Poulas K, Tzartos SJ. Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties. Biochim Biophys Acta.; 1794(2):355-66.

2008

  • Zisimopoulou P, Lagoumintzis G, Kostelidou K, Bitzopoulou K, Kordas G, TrakasN, Poulas K, Tzartos SJ. Towards antigen-specific apheresis of pathogenic autoantibodies as a further step in the treatment of myasthenia gravis by plasmapheresis. J Neuroimmunol; 15;201-202:95-103.
  • Zisimopoulou P, Lagoumintzis G, Poulas K, Tzartos SJ. Antigen-specific apheresis of human anti-acetylcholine receptor autoantibodies from myasthenia gravis patients' sera using Escherichia coli-expressed receptor domains. J Neuroimmunol; 30;200(1-2):133-41.
  • Tzartos SJ, Bitzopoulou K, Gavra I, Kordas G, Jacobson L, Kostelidou K, Lagoumintzis G, Lazos O, Poulas K, Sideris S, Sotiriadis A, Trakas N, Zisimopoulou P. Antigen-specific apheresis of pathogenic autoantibodies from myasthenia gravis sera. Ann N Y Acad Sci; 1132:291-9.
  • Bitzopoulou K, Kostelidou K, Poulas K, Tzartos SJ. Mutant forms of the extracellular domain of the human acetylcholine receptor gamma-subunit with improved solubility and enhanced antigenicity. The importance of the Cys-loop. Biochim Biophys Acta; 1784(9):1226-33
  • Konstantakaki M, Tzartos SJ, Poulas K, Eliopoulos E. Model of the extracellular domain of the human alpha7 nAChR based on the crystal structure of the mouse alpha1 nAChR extracellular domain. J Mol Graph Model; 26(8):1333-7.

2007

  • Zouridakis M, Kostelidou K, Sotiriadis A, Stergiou C, Eliopoulos E, Poulas K, Tzartos SJ. Circular dichroism studies of extracellular domains of human nicotinic acetylcholine receptors provide an insight into their structure. Int J Biol Macromol; 41(4):423-9.
  • Kalamida D, Poulas K, Avramopoulou V, Fostieri E, Lagoumintzis G, Lazaridis K, Sideri A, Zouridakis M, Tzartos SJ. Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity. FEBS J; 274(15):3799-845
  • Sideris S, Lagoumintzis G, Kordas G, Kostelidou K, Sotiriadis A, Poulas K, Tzartos SJ. Isolation and functional characterization of anti-acetylcholine receptor subunit-specific autoantibodies from myasthenic patients: receptor loss in cell culture. J Neuroimmunol; 189(1-2):111-7.
  • Konstantakaki M, Tzartos SJ, Poulas K, Eliopoulos E. Molecular modeling of the complex between Torpedo acetylcholine receptor and anti-MIR Fab198. Biochem Biophys Res Commun; 356(3):569-75.
  • Kostelidou K, Trakas N, Tzartos SJ. Extracellular domains of the beta, gamma and epsilon subunits of the human acetylcholine receptor as immunoadsorbents for myasthenic autoantibodies: a combination of immunoadsorbents results in increased efficiency. J Neuroimmunol; 190(1-2):44-52.

2006

  • Kostelidou K, Trakas N, Zouridakis M, Bitzopoulou K, Sotiriadis A, Gavra I, Tzartos SJ. Expression and characterization of soluble forms of the extracellular domains of the beta, gamma and epsilon subunits of the human muscle acetylcholine receptor. FEBS J; 273(15):3557-68.

2005

  • Fostieri E, Tzartos SJ, Berrih-Aknin S, Beeson D, Mamalaki A. Isolation of potent human Fab fragments against a novel highly immunogenic region on human muscle acetylcholine receptor which protect the receptor from myasthenic autoantibodies. Eur J Immunol; 35(2):632-43.
  • Protopapadakis E, Kokla A, Tzartos SJ, Mamalaki A. Isolation and characterization of human anti-acetylcholine receptor monoclonal antibodies from  transgenic mice expressing human immunoglobulin loci. Eur J Immunol; 35(6):1960-8.
  • Poëa-Guyon S, Christadoss P, Le Panse R, Guyon T, De Baets M, Wakkach A, Bidault J, Tzartos S, Berrih-Aknin S. Effects of cytokines on acetylcholine receptor expression: implications for myasthenia gravis. J Immunol; 174(10):5941-9.
  • Psaridi-Linardaki L, Trakas N, Mamalaki A, Tzartos SJ. Specific immunoadsorption of the autoantibodies from myasthenic patients using the extracellular domain of the human muscle acetylcholine receptor alpha-subunit. Development of an antigen-specific therapeutic strategy. J Neuroimmunol; 159(1-2):183-91.

2004

  • Avramopoulou V, Mamalaki A, Tzartos SJ. Soluble, oligomeric, and ligand-binding extracellular domain of the human alpha7 acetylcholine receptor expressed in yeast: replacement of the hydrophobic cysteine loop by the hydrophilic loop of the ACh-binding protein enhances protein solubility. J Biol Chem; 279(37):38287-93.

2003

  • Psaridi-Linardaki L, Mamalaki A, Tzartos SJ. Future therapeutic strategies in autoimmune myasthenia gravis. Ann N Y Acad Sci; 998:539-48.
  • Stassen MH, Machiels BM, Fostieri E, Tzartos SJ, Berrih-Aknin S, Bosmans E, Parren PW, De Baets MH. Characterization of a fully human IgG1 reconstructed from an anti-AChR Fab. Ann N Y Acad Sci; 998:399-400
  • Phan-Chan-Du A, Hemmerlin C, Krikorian D, Sakarellos-Daitsiotis M, Tsikaris V, Sakarellos C, Marinou M, Thureau A, Cung MT, Tzartos SJ. Solution conformation of the antibody-bound tyrosine phosphorylation site of the nicotinic acetylcholine receptor beta-subunit in its phosphorylated and nonphosphorylated states. Biochemistry; 42(24):7371-80.
  • Marinou M, Tzartos SJ. Identification of regions involved in the binding of alpha-bungarotoxin to the human alpha7 neuronal nicotinic acetylcholine receptor using synthetic peptides. Biochem J; 372(Pt 2):543-54.
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ΕΡΓΑΣΤΗΡΙΟ ΜΟΡΙΑΚΗΣ ΒΙΟΛΟΓΙΑΣ & ΑΝΟΣΟΛΟΓΙΑΣ, ΠΑΝΕΠΙΣΤΗΜΙΟ ΠΑΤΡΩΝ, 26504 ΡΙΟ, ΕΛΛΑΔΑ

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